One For The Money has a number of links to Grey's Anatomy, the ABC medical drama in which Katherine played Dr. Isobel 'Izzie' Stevens for 6 seasons - winning an Emmy and two Golden Globe nominations for her performances.

Both Jason O'Mara, who plays Joe Morelli and Debra Monk who plays Mrs. Plum, appeared in the show during Katherine's tenure and Daniel Sunjata who plays Ranger is a current guest star. One For The Money director Julie Anne Robinson also helmed several episodes of the TV show.

With such strong links between the two productions, E! News asked Katherine if she would consider returning to the small screen to bring up-to-date the storyline of her character who left abruptly after splitting with husband Alex Karev, played by Justin Chambers. Watch the clip to find out what she had to say.